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Several plausible mechanisms have been proposed for the glucose-lowering effects in type-2 diabetes, including effects on insulin sensitivity and secretion, changes in bile acid composition, and incretin effects.
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As a result, it starts working in minutes, which allows one to take insulin and eat right away.
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Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.
Patients with longstanding type-2 diabetes may already have complications; therefore, tight blood glucose management in this population might not provide the same degree of benefits compared with newly diagnosed type-2 diabetes and may be detrimental in patients at risk for hypoglycemia.
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So, about two weeks ago, my doctor ordered the Levemir insulin pen for me to add to the treatment plan.
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The A1c is a test that appeals to busy doctors who don't want to have to look at blood sugar logs, but it is not anywhere as predictive as actual blood sugar levels.
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About two-thirds of body cells require insulin to absorb glucose and in its absence, they will not be able to use the glucose (blood sugar) for energy.
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It is not known whether this medication passes into breast milk or if it could harm a nursing baby.
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DRUG INTERACTIONS: See also How to Use section.
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If you have trouble sleeping at night because you frequently have to get up to pee, it might be better to take your metformin before 3 PM because metformin may increase your need to pee at night.
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In healthy subjects, the time to reach maximal effect (minimum blood glucose concentrations) was approximately 2 to 3 hours after single oral doses of Glimepiride.
Glimepiride is removed from your body by your kidneys.
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Hypoglycemia or low blood sugar (usually minor if caught in time but can be serious or fatal if not treated; symptoms include profuse sweating, tremor, shakiness, dizziness, hunger.
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